Alizarine Red! It is a specific stain for calcium deposits.

Mineral depositions are one of the most common complications and troublesome causes of primary failure of a bioprosthetic cardiac valve after its implantation. Such deposits can cause significant damage to the bioprosthetic leaflet (L) as shown here. Calcification leads to leaflet stiffening with valve stenosis or possibly rupture with incompetence.

Alizarine Red, original magnification: x2, scale bar: 500 µm.
L: Bioprosthetic leaflet
*Calcium deposits

This histopathology image is one example from the comprehensive suite of Pathology Services offered by IMMR’s in-house team of Board-certified Veterinary Pathologists.

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